Intraosseous infusion of ice cold saline is less efficacious than intravenous infusion for induction of mild therapeutic hypothermia in a swine model of cardiac arrest

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Optimization of induction of mild therapeutic hypothermia with cold saline infusion: A laboratory experiment.

Cold fluid infusions can be used to induce mild therapeutic hypothermia after cardiac arrest. Fluid temperature higher than 4°C can increase the volume of fluid needed, prolong the induction phase of hypothermia and thus contribute to complications. We performed a laboratory experiment with two objectives. The first objective was to analyze the effect of wrapping fluid bags in ice packs on the ...

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Prehospital induction of mild hypothermia with cold normal saline for cardiac arrest: more harm than good?

Methods Objective: To determine whether prehospital cooling improves outcomes after resuscitation from cardiac arrest in patients with ventricular fibrillation (VF) and without VF. Design: A randomized clinical trial that assigned adults with prehospital cardiac arrest to standard care with or without prehospital cooling. Patient follow-up was completed by May 1, 2013. Nearly all of the patient...

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Cold saline infusion and ice packs alone are effective in inducing and maintaining therapeutic hypothermia after cardiac arrest.

AIM OF THE STUDY Hypothermia treatment with cold intravenous infusion and ice packs after cardiac arrest has been described and used in clinical practice. We hypothesised that with this method a target temperature of 32-34 degrees C could be achieved and maintained during treatment and that rewarming could be controlled. MATERIALS AND METHODS Thirty-eight patients treated with hypothermia aft...

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The feasibility of inducing mild therapeutic hypothermia after cardiac resuscitation using iced saline infusion via an intraosseous needle.

OBJECTIVE This study was done, using a swine model of prolonged ventricular fibrillation out-of-hospital cardiac arrest, to determine the feasibility of inducing therapeutic hypothermia after successful resuscitation by giving an intraosseous infusion of iced saline. METHODS This study was IACUC approved. Liter bags of normal saline, after being refrigerated for at least 24h, were placed in a...

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Effects of large volume, ice-cold intravenous fluid infusion on respiratory function in cardiac arrest survivors.

International guidelines for cardiopulmonary resuscitation recommend mild hypothermia (32-34 degrees C) for 12-24h in comatose survivors of cardiac arrest. To induce therapeutic hypothermia a variety of external and intravascular cooling devices are available. A cheap and effective method for inducing hypothermia is the infusion of large volume, ice-cold intravenous fluid. There are concerns re...

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ژورنال

عنوان ژورنال: Resuscitation

سال: 2011

ISSN: 0300-9572

DOI: 10.1016/j.resuscitation.2011.01.007